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Viser: Alginate Fibers and Wound Dressings - Seaweed Derived Natural Therapy

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Alginate Fibers and Wound Dressings Vital Source e-bog

Yimin Qin
(2023)
John Wiley & Sons
1.421,00 kr.
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Alginate Fibers and Wound Dressings - Seaweed Derived Natural Therapy

Alginate Fibers and Wound Dressings

Seaweed Derived Natural Therapy
Yimin Qin
(2023)
Sprog: Engelsk
John Wiley & Sons, Limited
1.555,00 kr.
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Detaljer om varen

  • 1. Udgave
  • Vital Source searchable e-book (Reflowable pages)
  • Udgiver: John Wiley & Sons (August 2023)
  • ISBN: 9783527845194
Alginate Fibers and Wound Dressings

Comprehensive resource on the science and research behind alginate fibers, along with their many functional applications in different fields

Alginate Fibers and Wound Dressings: Seaweed Derived Natural Therapy offers a general introduction to the sources of alginate and the production methods for alginate fibers and wound dressings, in addition to the novel properties and applications of these functional materials in wound management. Taking into consideration of the latest results of clinical researches conducted around the world, this book summarizes the unique properties of alginate wound dressings, including their ‘gel blocking’ properties and the ability to promote wound healing, facilitate haemostasis, reduce pain, suppress bacteria growth, and lower treatment cost in the treatment of a wide range of wounds, including leg ulcers, burn wounds, pressure sores, surgical wounds, and many other types of wounds with high levels of exudates.

Sample topics covered in Alginate Fibers and Wound Dressings include:

  • Why alginate fibers can be used as a carrier to deliver zinc, copper, silver, and other bioactive metal ions
  • How alginate wound dressings can help maintain a physiologically moist microenvironment that promotes healing and the formation of granulation tissue
  • Unique properties of alginate fibers that are highly useful for functional textile materials and medical textile products, such as gel forming properties when in contact with body fluid
  • Other excellent performance characteristics of alginate fibers, such as haemostatic, antimicrobial, skin whitening, and many other unique bioactivities

Providing comprehensive coverage of the subject, Alginate Fibers and Wound Dressings is an essential resource for students, researchers, and professionals involved in professions and programs of study that intersect with the subject.

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Detaljer om varen

  • Hardback: 256 sider
  • Udgiver: John Wiley & Sons, Limited (Oktober 2023)
  • ISBN: 9783527353293
Author Biography xiii Preface xv 1 The Extraction of Alginate from Brown Seaweeds 1
1.1 Introduction 1
1.2 Global Distribution of Brown Seaweeds 2
1.3 The Extraction of Alginate from Brown Seaweeds 6
1.3.1 General Description of the Extraction Process 6
1.3.2 A Comparison of Alginic Acid Method and Calcium Alginate Method 9
1.3.3 Process Control 9
1.3.4 Key Process Parameters 10
1.3.4.1 Size Reduction of Raw Materials 10
1.3.4.2 Acid Treatment 10
1.3.4.3 Formaldehyde Treatment 12
1.3.4.4 Alkaline Extraction 12
1.3.4.5 Separation of Alginate from Insoluble Seaweed Residue 12
1.4 Ultrapure Alginate 14
1.5 Summary 15 References 15 Further Reading 17 2 Chemical, Physical, and Biological Properties of Alginic Materials 19
2.1 Introduction 19
2.2 The Chemical Structure of Alginic Acid 19
2.2.1 Early Studies and Basic Structural Feature 19
2.2.2 M/G Ratio and Distribution 20
2.2.3 C-5 Epimerization and Designer Alginate 21
2.2.4 Molecular Weight and Distribution 22
2.2.5 Chemical Stability 22
2.3 Physical Properties of Alginic Materials 24
2.4 Viscosity of Alginate Solutions 26
2.4.1 Effect of Molecular Weight on Solution Viscosity 26
2.4.2 Effect of Concentration on Solution Viscosity 27
2.4.3 Effect of Temperature on Solution Viscosity 28
2.4.4 Effect of Shear Rate on Solution Viscosity 28
2.4.5 Effect of Salt on Solution Viscosity 28
2.4.6 Effect of pH on Solution Viscosity 29
2.5 Polyelectrolyte Properties 29
2.6 The Ion-Exchange Properties of Alginate 29
2.7 Gelling Properties of Alginate 31
2.8 Film-Forming Properties 32
2.9 Fiber-Forming Properties 33
2.10 Bioactivities of Alginic Materials 33
2.10.1 Enzyme Inhibition Activities of Alginate 33
2.10.2 Biocompatibility and Cell Activities of Alginate 34
2.11 Summary 35 References 35 3 Industrial Applications of Alginic Materials 39
3.1 Introduction 39
3.2 Functional Properties of Alginic Material 39
3.2.1 Alginate as a Thickening Agent 39
3.2.2 Alginate as a Gelling Agent 40
3.2.3 Alginate as a Film-Forming Agent 40
3.2.4 Alginate as a Stabilizer 41
3.2.5 Alginate for Encapsulation and Immobilization 41
3.3 Industrial Applications of Alginate 42
3.3.1 Food Ingredients 42
3.3.2 Medical and Pharmaceutical Uses 44
3.3.2.1 Dental Impression 44
3.3.2.2 Therapeutic Cell Entrapment 45
3.3.2.3 Controlled Release of Drugs 45
3.3.2.4 Alginate Oligoelectrolytes as a Mucin Polymer Network Modifier 45
3.3.2.5 Oligoguluronates as Modifiers of Cystic Fibrosis Mucus 45
3.3.3 Wound Dressings and Hemostatic Agent 46
3.3.4 Immobilization of Biocatalysts 46
3.3.5 Controlled Release of Active Agents 48
3.3.6 Textile Printing Paste 48
3.3.7 Sizing Agent for Paper 48
3.3.8 Coating for Welding Rods 49
3.3.9 Binders for Fish Feed 50
3.3.10 Biostimulants 50
3.4 Summary 50 References 51 4 The Production of Fibers From Alginate 57
4.1 Introduction 57
4.2 The Properties of Alginate as a Fiber-Forming Polymer 58
4.3 Preparation of the Spinning Solutions 60
4.3.1 Molecular Weight of the Alginate Powder 60
4.3.2 Concentration of the Spinning Solution 61
4.3.3 Temperature of the Spinning Solution 61
4.3.4 pH of the Spinning Solution 61
4.4 The Production of Calcium Alginate Fibers 61
4.5 The Production of Calcium Sodium Alginate Fibers 65
4.6 The Production of Sodium Alginate Fibers 66
4.7 The Production of Alginic Acid Fibers 68
4.8 The Production of Zinc Alginate Fibers 69
4.9 The Production of Alginate Fibers Containing Pectin and Carboxymethyl Cellulose 69
4.10 The Production of Silver-Containing Alginate Fibers 71
4.11 The Production of Other Novel Alginate Fibers 73
4.12 Historical Development of Alginate Fibers 76
4.13 Summary 78 References 78 5 Ion-Exchange and Gel-Forming Properties of Alginate Fibers 83
5.1 Introduction 83
5.2 Characterization Methods for Ion Exchange and Gel Forming Properties 83
5.3 Ion-Exchange Properties of Alginate Fibers 86
5.3.1 Ion-Exchange Between Calcium Alginate Fibers and Sodium Ions 86
5.3.2 Ion-Exchange Between Alginate Fibers and Zinc Ions 87
5.3.3 Ion-Exchange Between Alginate Fibers and Copper Ions 91
5.4 Gelling Properties of Alginate Fibers 94
5.5 Summary 98 References 99 6 Applications of Alginate Fibers as Smart Woundcare Materials 101
6.1 Introduction 101
6.2 Functional Requirements of the Wound Dressings 103
6.3 Modern Advanced Wound Dressings 106
6.3.1 Chitin and Chitosan Fibers and Wound Dressings 107
6.3.2 Superabsorbent Cellulosic Fibers 108
6.3.3 Polyurethane Film and Foam 109
6.3.4 Hydrogels 110
6.3.5 Hydrocolloids 111
6.3.6 Activated Carbon 112
6.3.7 Low Adherent Dressings 113
6.3.8 Composite Wound Care Products 114
6.3.9 Antimicrobial Wound Dressings 116
6.3.10 Interactive Dressings 117
6.3.11 Tissue-Engineered "Skin Equivalents" 117
6.3.12 Cell-Containing Matrices 117
6.4 Applications of Alginate Fibers in Functional Wound Dressings 118
6.5 Development of Alginate Wound Dressings 119
6.6 Summary 121 References 123 Further Reading 124 7 Absorption and Interactive Properties of Alginate Wound Dressings 125
7.1 Introduction 125
7.2 Characterization Methods 126
7.2.1 Test on Absorbency 126
7.2.2 Fiber Calcium and Sodium Contents 127
7.2.3 Gel Swelling 127
7.2.4 Wet Integrity 127
7.2.5 Wicking Behavior 127
7.2.6 Dry and Wet Strength 128
7.3 Absorption of Wound Fluid by Alginate-Based Wound Dressings 128
7.3.1 Absorption Mechanism of Alginate Wound Dressings 128
7.3.2 Absorbency of the Various Types of Alginate Wound Dressings 129
7.3.3 Fluid Retention Between Fibers and Inside Fibers 130
7.3.4 A Comparison of Absorption Properties Between Alginate Felt and Rope 131
7.3.5 Effect of Sterilization on the Absorption Properties of Alginate Dressings 131
7.3.6 Effect of Guluronate and Mannuronate Contents 132
7.3.7 Effect of Calcium and Sodium Contents 133
7.3.8 Effect of Nonwoven Structures 133
7.3.9 Effect of Adding CMC Into the Alginate Fibers 134
7.3.10 Wicking of Fluid 135
7.3.11 Dry and Wet Strength 137
7.4 Interactive Properties of Alginate Wound Dressings 138
7.4.1 Interactive Moisture Handling Properties of Alginate Wound Dressings 138
7.4.2 Biologically Interactive Properties of Alginate Wound Dressings 138
7.4.3 Enzyme Inhibition Properties of Alginate Wound Dressings 139
7.5 Summary 142 References 143 8 Clinical Applications of Alginate Wound Dressings 145
8.1 Introduction 145
8.2 Biocompatibility and Bioactivities of Alginate Wound Dressings 145
8.3 Wound Healing Mechanisms of Alginate Wound Dressings 147
8.4 Clinical Applications of Alginate Wound Dressings 148
8.4.1 Applications of Alginate Wound Dressings in Pressure Ulcers 149
8.4.2 Applications of Alginate Wound Dressings in Leg Ulcers 149
8.4.3 Applications of Alginate Wound Dressings in Diabetic Foot Ulcers 151
8.4.4 Applications of Alginate Wound Dressings in Burn Wounds and Donor Sites 151
8.4.5 Applications of Alginate Wound Dressings as a Hemostatic Agent for Bleeding Wounds 154
8.4.6 Applications of Alginate Wound Dressings in Surgical Wounds 156
8.4.7 Applications of Alginate Wound Dressings in Nose Surgery 158
8.4.8 Applications of Alginate Wound Dressings in Anal Fistula Surgery 159
8.4.9 Applications of Alginate Wound Dressings in Cavity Wounds 160
8.4.10 Applications of Alginate-Based Composite Wound Dressings 160
8.5 Main Properties of Alginate Wound Dressings 160
8.5.1 Wound-Healing Promotion 161
8.5.2 The Hemostatic Properties of Alginate Wound Dressing 162
8.5.3 Pain Relief Properties of Alginate Wound Dressing 162
8.5.4 The Antimicrobial Properties of Alginate Wound Dressing 163
8.5.5 Alginate Wound Dressings as Cavity Filler 163
8.5.6 Cost-Effectiveness of Alginate Wound Dressings 163
8.6 Summary 163 References 163 9 Functional Modifications of Alginate Fibers and Wound Dressings 169
9.1 Introduction 169
9.2 Chemical Modification of Alginic Acid 169
9.2.1 Chemical Modification of the Hydroxyl Groups 170
9.2.1.1 Oxidation 170
9.2.1.2 Reductive-Amination of Oxidized Alginate 171
9.2.1.3 Sulfation 172
9.2.1.4 Cyclodextrin-Linked Alginate 172
9.2.1.5 Acetylation of Alginate 172
9.2.1.6 Phosphorylation of Alginates 173
9.2.2 Chemical Modification of the Carboxyl Groups 173
9.2.2.1 Esterification 173
9.2.2.2 Amidation 174
9.2.3 Other Chemical Modifications 175
9.2.3.1 Organic Soluble Derivative of Alginate 175
9.2.3.2 Attachment of Cell Signaling Molecules 175
9.2.3.3 Covalent Cross-linking of Alginates 176
9.2.3.4 Graft Copolymerization of Alginates 177
9.3 Innovations in the Fiber-Making Process 178
9.3.1 The Production of Alginate Fibers Containing Metal Ions and Inorganic Compounds 179
9.3.2 The Production of Polyblend Fibers of Alginate and Other Polymers 180
9.3.3 The Pr
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