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Viser: Iron in Biology - Molecular Structures, Cellular Processes and Living Systems
Iron in Biology Vital Source e-bog
Yoshitsugu Shiro
(2025)
Iron in Biology
Molecular Structures, Cellular Processes and Living Systems
Yoshitsugu Shiro, Hitomi Sawai og Takehiko Tosha
(2025)
Sprog: Engelsk
om ca. 15 hverdage
Detaljer om varen
- 1. Udgave
- Vital Source searchable e-book (Reflowable pages)
- Udgiver: Royal Society of Chemistry (Juni 2025)
- ISBN: 9781837677986
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Detaljer om varen
- Hardback: 372 sider
- Udgiver: Royal Society of Chemistry, The (Juni 2025)
- Forfattere: Yoshitsugu Shiro, Hitomi Sawai og Takehiko Tosha
- ISBN: 9781837674404
Heavy metals essential to organisms are termed "biometals". Bio-inorganic chemistry deals with the functions of biometals in vivo at an atomic to molecular level, while cellular regulation of biometals such as absorption and transport has been investigated in cell biology. Although these research fields are independently developed and matured, interdisciplinary information across these fields is required for a comprehensive understanding of the roles of biometals at atomic to molecular, cellular and organism levels.
This book focuses on iron (Fe) in cells, since it is the most abundant metal in living system and is involved in a variety of physiological events such as enzymatic reactions as catalysts and signal transduction. Both excess and shortage of iron cause serious diseases such as anaemia, cancer and neuronal degeneration. The cellular systems consisting of many specific proteins strictly control the iron contents through the iron dynamics in cells including absorption, sensing, storage, transport and usage.
Resulting from a 5-year project on Integrated Biometal Science in Japan, this book not only documents the latest research but also fills a gap between chemical understanding and our real life, by providing fundamental ideas on genetics, drugs and environmental health.