SØG - mellem flere end 8 millioner bøger:
Viser: Clinical Pharmacokinetics and Pharmacodynamics - Concepts and Applications
Clinical Pharmacokinetics and Pharmacodynamics
Concepts and Applications
Malcolm Rowland og Thomas N. Tozer
(2010)
Sprog: Engelsk
Lippincott Williams & Wilkins
1.145,00 kr.
Denne titel er udgået og kan derfor ikke bestilles. Vi beklager.
Detaljer om varen
- Hardback: 864 sider
- Udgiver: Lippincott Williams & Wilkins (Februar 2010)
- Forfattere: Malcolm Rowland og Thomas N. Tozer
- ISBN: 9780781750097
Formerly "Clinical Pharmacokinetics: Concepts and Clinical Applications, " this fully updated Fourth Edition has been retitled "Pharmacokinetics and Pharmacodynamics: Concepts and Clinical Applications" to reflect the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This revised edition also reflects the explosion in our understanding at the molecular and mechanistic levels of all the processes controlling the pharmacokinetics of drugs. The text is authored by two leading international experts on the clinical aspects of pharmacokinetics/pharmacodynamics and is widely considered one of the authoritative texts on the subject.
Preface Definition of Symbols Non-Proprietary and Brand Names of Drugs in Text and Illustrations I. Basic Considerations
1. Therapeutic Relevance
2. Fundamental Concepts and Terminology II. Exposure and Response after a Single Dose
3. Kinetics Following an Intravenous Bolus Dose
4. Membranes and Distribution
5. Elimination
6. Kinetics Following an Extravascular Dose
7. Absorption
8. Response Following a Single Dose III. Therapeutic Regimens
9. Therapeutic Window
10. Constant-Rate Input
11. Multiple Dose Regimens IV. Individualization
12.Variability
13.Genetics
14. Age, Weight, and Gender
15. Disease
16. Nonlinearities
17. Drug Interactions
18. Initiating and Managing Therapy V. Supplemental Topics
19. Distribution Kinetics
20. Metabolites and Drug Response
21. New! Protein Drugs
22. New! Prediction and Refinement of Human Kinetics from In Vitro, Preclinical, and Early Clinical Data Appendices A. Assessment of AUC B. Ionization and the pH Partition Hypothesis C. Distribution of Drugs Extensively Bound to Plasma Proteins D. Plasma-to-Blood Concentration Ratio E. Well-stirred Model of Hepatic Clearance F. Absorption Kinetics G. Wagner-Nelson Method H. Mean Residence Time I. Amount of Drug in Body on Accumulation to Plateau J. Answers to Study Problems
1. Therapeutic Relevance
2. Fundamental Concepts and Terminology II. Exposure and Response after a Single Dose
3. Kinetics Following an Intravenous Bolus Dose
4. Membranes and Distribution
5. Elimination
6. Kinetics Following an Extravascular Dose
7. Absorption
8. Response Following a Single Dose III. Therapeutic Regimens
9. Therapeutic Window
10. Constant-Rate Input
11. Multiple Dose Regimens IV. Individualization
12.Variability
13.Genetics
14. Age, Weight, and Gender
15. Disease
16. Nonlinearities
17. Drug Interactions
18. Initiating and Managing Therapy V. Supplemental Topics
19. Distribution Kinetics
20. Metabolites and Drug Response
21. New! Protein Drugs
22. New! Prediction and Refinement of Human Kinetics from In Vitro, Preclinical, and Early Clinical Data Appendices A. Assessment of AUC B. Ionization and the pH Partition Hypothesis C. Distribution of Drugs Extensively Bound to Plasma Proteins D. Plasma-to-Blood Concentration Ratio E. Well-stirred Model of Hepatic Clearance F. Absorption Kinetics G. Wagner-Nelson Method H. Mean Residence Time I. Amount of Drug in Body on Accumulation to Plateau J. Answers to Study Problems
De oplyste priser er inkl. moms
Butikker og åbningstid
Handler du som firma
Forretningsbetingelser
Porto og forsendelse
Data & cookiepolitik
Handler du som firma
Forretningsbetingelser
Porto og forsendelse
Data & cookiepolitik
Find pensumliste
FAQ for studerende
Pensumlistegaranti
Sortiment og levering
Kompendier(for undervisere)
FAQ for studerende
Pensumlistegaranti
Sortiment og levering
Kompendier(for undervisere)
Polyteknisk Boghandel og Forlag A/S - Anker Engelundsvej 1 - 2800 Lyngby
Tlf 77 42 43 44 - email poly@polyteknisk.dk - CVR 34072655 - Sydbank Reg: 6748 Konto 0001107927
Tlf 77 42 43 44 - email poly@polyteknisk.dk - CVR 34072655 - Sydbank Reg: 6748 Konto 0001107927